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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50434701'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50434701
PNG
(CHEMBL2385183)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5ccccc5Cl)c5cc(F)ccc5c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C40H36ClF2N5O5/c1-24-13-17-47(18-14-24)16-5-19-52-37-23-31-28(22-36(37)51-2)34(12-15-44-31)53-35-11-9-26(21-30(35)43)45-40(50)38-39(49)27-10-8-25(42)20-33(27)48(46-38)32-7-4-3-6-29(32)41/h3-4,6-12,15,20-24H,5,13-14,16-19H2,1-2H3,(H,45,50)
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Similars
Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem 21: 2843-55 (2013)


Article DOI: 10.1016/j.bmc.2013.04.013
BindingDB Entry DOI: 10.7270/Q25D8T6Z
More data for this
Ligand-Target Pair