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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50434705'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50434705
PNG
(CHEMBL2385196)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cccc(c5)C(F)(F)F)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCCC1
Show InChI InChI=1S/C39H33F4N5O5/c1-51-34-22-28-30(23-35(34)52-19-7-18-47-16-4-5-17-47)44-15-14-32(28)53-33-13-12-25(21-29(33)40)45-38(50)36-37(49)27-10-2-3-11-31(27)48(46-36)26-9-6-8-24(20-26)39(41,42)43/h2-3,6,8-15,20-23H,4-5,7,16-19H2,1H3,(H,45,50)
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Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem 21: 2843-55 (2013)


Article DOI: 10.1016/j.bmc.2013.04.013
BindingDB Entry DOI: 10.7270/Q25D8T6Z
More data for this
Ligand-Target Pair