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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50434707'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50434707
PNG
(CHEMBL2385179)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cc(C)ccc5C)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C40H38FN5O6/c1-25-9-10-26(2)33(21-25)46-32-8-5-4-7-28(32)39(47)38(44-46)40(48)43-27-11-12-35(30(41)22-27)52-34-13-14-42-31-24-37(36(49-3)23-29(31)34)51-18-6-15-45-16-19-50-20-17-45/h4-5,7-14,21-24H,6,15-20H2,1-3H3,(H,43,48)
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Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem 21: 2843-55 (2013)


Article DOI: 10.1016/j.bmc.2013.04.013
BindingDB Entry DOI: 10.7270/Q25D8T6Z
More data for this
Ligand-Target Pair