Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50434711'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50434711 (CHEMBL2385193) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5c(Cl)cccc5Cl)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 |(48.04,-29.9,;48.04,-31.44,;49.37,-32.21,;50.7,-31.44,;52.04,-32.21,;53.36,-31.43,;53.36,-29.89,;54.68,-29.12,;56.01,-29.88,;57.34,-29.11,;57.33,-27.57,;58.66,-26.79,;60,-27.55,;60.01,-29.09,;61.33,-26.77,;61.32,-25.24,;62.66,-24.46,;62.66,-22.92,;61.32,-22.16,;60,-22.94,;61.31,-20.64,;62.65,-19.85,;64,-20.59,;63.99,-22.13,;65.33,-22.9,;63.99,-25.23,;65.32,-24.44,;66.66,-25.21,;66.67,-26.77,;65.33,-27.54,;63.99,-26.77,;62.67,-27.54,;62.68,-29.08,;55.99,-26.8,;54.66,-27.59,;53.32,-26.83,;54.7,-32.19,;54.71,-33.74,;53.37,-34.52,;52.04,-33.75,;50.71,-34.53,;49.37,-33.76,;48.04,-34.53,;46.7,-33.75,;45.37,-34.52,;44.04,-33.75,;44.04,-32.21,;45.37,-31.44,;45.38,-29.91,;44.05,-29.13,;44.06,-27.59,;42.71,-29.9,;42.7,-31.44,)| Show InChI InChI=1S/C40H36Cl2FN5O5/c1-24-14-18-47(19-15-24)17-6-20-52-36-23-31-27(22-35(36)51-2)33(13-16-44-31)53-34-12-11-25(21-30(34)43)45-40(50)37-39(49)26-7-3-4-10-32(26)48(46-37)38-28(41)8-5-9-29(38)42/h3-5,7-13,16,21-24H,6,14-15,17-20H2,1-2H3,(H,45,50)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 21: 2843-55 (2013) Article DOI: 10.1016/j.bmc.2013.04.013 BindingDB Entry DOI: 10.7270/Q25D8T6Z
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