BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50434714'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50434714
PNG
(CHEMBL2385190)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nn(-c5cccc(c5)C(F)(F)F)c5ccccc5c4=O)cc3F)ccnc2cc1OCCCN1CCC(C)CC1
Show InChI InChI=1S/C41H37F4N5O5/c1-25-14-18-49(19-15-25)17-6-20-54-37-24-32-30(23-36(37)53-2)34(13-16-46-32)55-35-12-11-27(22-31(35)42)47-40(52)38-39(51)29-9-3-4-10-33(29)50(48-38)28-8-5-7-26(21-28)41(43,44)45/h3-5,7-13,16,21-25H,6,14-15,17-20H2,1-2H3,(H,47,52)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.10n/an/an/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay


Bioorg Med Chem 21: 2843-55 (2013)


Article DOI: 10.1016/j.bmc.2013.04.013
BindingDB Entry DOI: 10.7270/Q25D8T6Z
More data for this
Ligand-Target Pair