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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50437165'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50437165
PNG
(CHEMBL2401827)
Show SMILES CNC(=O)c1coc2c(O[C@H](C)c3c(Cl)ccc(F)c3Cl)c(N)ncc12 |r|
Show InChI InChI=1S/C17H14Cl2FN3O3/c1-7(12-10(18)3-4-11(20)13(12)19)26-15-14-8(5-23-16(15)21)9(6-25-14)17(24)22-2/h3-7H,1-2H3,(H2,21,23)(H,22,24)/t7-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 590n/an/an/an/an/an/a



OSI Pharmaceuticals, LLC

Curated by ChEMBL


Assay Description
Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 mins


Bioorg Med Chem Lett 23: 4381-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.05.074
BindingDB Entry DOI: 10.7270/Q2RB7601
More data for this
Ligand-Target Pair