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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50510590'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50510590
PNG
(CHEMBL4545574)
Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccccc4)cc3)c2cc1OC
Show InChI InChI=1S/C25H23N3O6S/c1-32-23-14-20-21(15-24(23)33-2)26-13-12-22(20)34-19-10-8-18(9-11-19)27-25(29)28-35(30,31)16-17-6-4-3-5-7-17/h3-15H,16H2,1-2H3,(H2,27,28,29)
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PC cid
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Article
PubMed
n/an/a 54n/an/an/an/an/an/a



School of Marine Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay

Bioorg Med Chem 27: 2801-2812 (2019)


Article DOI: 10.1016/j.bmc.2019.05.007
BindingDB Entry DOI: 10.7270/Q23F4SZM
More data for this
Ligand-Target Pair