Compile Data Set for Download or QSAR

Found 10 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50532755'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of wild type phosphorylated MET (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptide ad...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET in human MKN45 cells assessed as reduction in pMET Y1230/1234/1235 level incubated for 1 hr by ELISA				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET in human MKN45 cells assessed as reduction in pMET Y1230/1234/1235 level incubated for 1 hr by ELISA				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET M1250T mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET M1250T mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET L1195V mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET L1195V mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50532755 (CHEMBL4448029) Show SMILES Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccc(F)cc3)cc2s1 Show InChI InChI=1S/C18H11FN6S2/c19-11-3-1-10(2-4-11)13-7-8-16-22-23-18(25(16)24-13)26-12-5-6-14-15(9-12)27-17(20)21-14/h1-9H,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Germany GmbH Curated by ChEMBL					Assay Description Inhibition of phosphorylated MET Y1230H mutant (unknown origin) pre-incubated for 30 mins before biotinylated poly(glutamate-alanine-tyrosine) peptid...				J Med Chem 59: 7066-74 (2016) Article DOI: 10.1021/acs.jmedchem.6b00280 BindingDB Entry DOI: 10.7270/Q2WM1HW4
					More data for this Ligand-Target Pair