Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hexokinase-4' and Ligand = 'BDBM260397'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hexokinase-4 (Homo sapiens (Human))	BDBM260397 (US9527838, 25) Show SMILES Cn1cnnc1Sc1ccc(Sc2ccc(F)cc2)c(n1)C(=O)Nc1nc(CC(O)=O)c(Cl)s1 Show InChI InChI=1S/C20H14ClFN6O3S3/c1-28-9-23-27-20(28)33-14-7-6-13(32-11-4-2-10(22)3-5-11)16(25-14)18(31)26-19-24-12(8-15(29)30)17(21)34-19/h2-7,9H,8H2,1H3,(H,29,30)(H,24,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	18.6	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E. coli, and purified on ANTIFLAG M2 AFFINITY GEL (Sigma). The assay wa...				US Patent US9527838 (2016) BindingDB Entry DOI: 10.7270/Q2RV0MN1
					More data for this Ligand-Target Pair