Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A' and Ligand = 'BDBM135581'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM135581 (US8846654, 97) Show SMILES COc1ccc(Cn2c(=O)n(C3CCN(CC3)C=O)c3cc(Cl)cc(Cl)c3c2=O)cc1OC Show InChI InChI=1S/C23H23Cl2N3O5/c1-32-19-4-3-14(9-20(19)33-2)12-27-22(30)21-17(25)10-15(24)11-18(21)28(23(27)31)16-5-7-26(13-29)8-6-16/h3-4,9-11,13,16H,5-8,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	7.5	n/a
Sanofi US Patent					Assay Description The assay is carried out in 1.5 ml Eppendorf tubes comprising 40 mM of Tris-HCl (pH 7.5), 15 mM of MgCl2, 1 mM of EGTA, 0.5 mg/ml of bovine serum alb...				US Patent US8846654 (2014) BindingDB Entry DOI: 10.7270/Q21V5CPZ
					More data for this Ligand-Target Pair