Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A' and Ligand = 'BDBM50457961'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50457961 (CHEMBL4207233) Show SMILES Cn1c2nc(NCc3ccccn3)n(CCCC(=O)N\N=C\c3ccc(O)c(O)c3O)c2c(=O)n(C)c1=O Show InChI InChI=1S/C24H26N8O6/c1-30-21-18(22(37)31(2)24(30)38)32(23(28-21)26-13-15-6-3-4-10-25-15)11-5-7-17(34)29-27-12-14-8-9-16(33)20(36)19(14)35/h3-4,6,8-10,12,33,35-36H,5,7,11,13H2,1-2H3,(H,26,28)(H,29,34)/b27-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged PDE7A expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...				Eur J Med Chem 146: 381-394 (2018) Article DOI: 10.1016/j.ejmech.2018.01.068 BindingDB Entry DOI: 10.7270/Q2XD1496
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