Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A' and Ligand = 'BDBM130751'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Rattus norvegicus (Rat))	BDBM130751 (US8822448, 169) Show SMILES Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CCC(CC1)OC1CCC1 Show InChI InChI=1S/C26H32N4O4/c1-16-13-23-21(24-22(25(31)28-23)15-27-30(24)17-7-11-33-12-8-17)14-20(16)26(32)29-9-5-19(6-10-29)34-18-3-2-4-18/h13-15,17-19H,2-12H2,1H3,(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	8.0	n/a
Astellas Pharma Inc. US Patent					Assay Description The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo...				US Patent US8822448 (2014) BindingDB Entry DOI: 10.7270/Q2BK1B1J
					More data for this Ligand-Target Pair