Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM267420'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267420 (US9718822, 12 | US9750744, Example 12 | US9902741,...) Show SMILES Fc1cnc2NCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C18H18FN7O/c19-11-8-12-14-2-1-6-25(14)15-3-7-26-17(24-15)13(10-23-26)18(27)21-5-4-20-16(12)22-9-11/h3,7-10,14H,1-2,4-6H2,(H,20,22)(H,21,27)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.5	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9718822 (2017) BindingDB Entry DOI: 10.7270/Q2N3000J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267420 (US9718822, 12 | US9750744, Example 12 | US9902741,...) Show SMILES Fc1cnc2NCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C18H18FN7O/c19-11-8-12-14-2-1-6-25(14)15-3-7-26-17(24-15)13(10-23-26)18(27)21-5-4-20-16(12)22-9-11/h3,7-10,14H,1-2,4-6H2,(H,20,22)(H,21,27)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of Mississippi					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors Immulon 4HBX 384-well microtiter p...				J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q21N83FK
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267420 (US9718822, 12 | US9750744, Example 12 | US9902741,...) Show SMILES Fc1cnc2NCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C18H18FN7O/c19-11-8-12-14-2-1-6-25(14)15-3-7-26-17(24-15)13(10-23-26)18(27)21-5-4-20-16(12)22-9-11/h3,7-10,14H,1-2,4-6H2,(H,20,22)(H,21,27)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9750744 (2017) BindingDB Entry DOI: 10.7270/Q2C82CFX
					More data for this Ligand-Target Pair