Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM267421'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267421 (US9718822, 13 | US9750744, Example 13) Show SMILES Fc1cnc2NCCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C19H20FN7O/c20-12-9-13-15-3-1-7-26(15)16-4-8-27-18(25-16)14(11-24-27)19(28)22-6-2-5-21-17(13)23-10-12/h4,8-11,15H,1-3,5-7H2,(H,21,23)(H,22,28)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9750744 (2017) BindingDB Entry DOI: 10.7270/Q2C82CFX
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM267421 (US9718822, 13 | US9750744, Example 13) Show SMILES Fc1cnc2NCCCNC(=O)c3cnn4ccc(nc34)N3CCC[C@@H]3c2c1 |r| Show InChI InChI=1S/C19H20FN7O/c20-12-9-13-15-3-1-7-26(15)16-4-8-27-18(25-16)14(11-24-27)19(28)22-6-2-5-21-17(13)23-10-12/h4,8-11,15H,1-3,5-7H2,(H,21,23)(H,22,28)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.5	n/a
Array BioPharma, Inc. US Patent					Assay Description An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...				US Patent US9718822 (2017) BindingDB Entry DOI: 10.7270/Q2N3000J
					More data for this Ligand-Target Pair