Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM356073'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM356073 ((R)-N-(2-((2- aminopropanamido)methyl)-4- phenylpy...) Show SMILES C[C@@H](N)C(=O)NCc1ncc(NC(=O)c2cc(-c3ccn(C)n3)c(cc2F)C(F)(F)F)c(n1)-c1ccccc1 |r| Show InChI InChI=1S/C26H23F4N7O2/c1-14(31)24(38)33-13-22-32-12-21(23(35-22)15-6-4-3-5-7-15)34-25(39)17-10-16(20-8-9-37(2)36-20)18(11-19(17)27)26(28,29)30/h3-12,14H,13,31H2,1-2H3,(H,33,38)(H,34,39)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...				US Patent US9815846 (2017) BindingDB Entry DOI: 10.7270/Q20P129R
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