Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50384724'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50384724 (CHEMBL2037221) Show SMILES CCN(CC)CCNC(=O)c1c[nH]c(\C=C2/C(=O)Nc3cc(Nc4cccc(NC(=O)c5cc(cc(c5)C(F)(F)F)N5CCN(C)CC5)c4)ccc23)c1 Show InChI InChI=1S/C39H43F3N8O3/c1-4-49(5-2)12-11-43-36(51)26-18-31(44-24-26)22-34-33-10-9-30(23-35(33)47-38(34)53)45-28-7-6-8-29(21-28)46-37(52)25-17-27(39(40,41)42)20-32(19-25)50-15-13-48(3)14-16-50/h6-10,17-24,44-45H,4-5,11-16H2,1-3H3,(H,43,51)(H,46,52)(H,47,53)/b34-22-	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of TRKA by HTRF assay				ACS Med Chem Lett 3: 140-145 (2012) Article DOI: 10.1021/ml200261d BindingDB Entry DOI: 10.7270/Q2SJ1MNM
					More data for this Ligand-Target Pair