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Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM50391953'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50391953
PNG
(CHEMBL2152288)
Show SMILES Nc1cc(NS(=O)(=O)c2cccc(c2)C(F)(F)F)cc(c1)-c1cnc2[nH]cc(-c3ccncc3)c2c1
Show InChI InChI=1S/C25H18F3N5O2S/c26-25(27,28)18-2-1-3-21(11-18)36(34,35)33-20-9-16(8-19(29)12-20)17-10-22-23(14-32-24(22)31-13-17)15-4-6-30-7-5-15/h1-14,33H,29H2,(H,31,32)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.67n/an/an/an/an/an/a



Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL


Assay Description
Inhibition of TRKA assessed as [gamma33P]ATP incorporation into substrate


J Med Chem 55: 5337-49 (2012)


Article DOI: 10.1021/jm3002982
BindingDB Entry DOI: 10.7270/Q2JM2BQ3
More data for this
Ligand-Target Pair