Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor [441-796]' and Ligand = 'BDBM136645'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM136645 (US10005783, 62 | US10047097, 62 | US10774085, Exam...) Show SMILES Fc1ccc(F)c(c1)[C@H]1CCCN1c1ccn2ncc(NC(=O)c3cc(Cl)ccn3)c2n1 |r| Show InChI InChI=1S/C22H17ClF2N6O/c23-13-5-7-26-17(10-13)22(32)28-18-12-27-31-9-6-20(29-21(18)31)30-8-1-2-19(30)15-11-14(24)3-4-16(15)25/h3-7,9-12,19H,1-2,8H2,(H,28,32)/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	n/a
Array BioPharma, Inc. US Patent					Assay Description Immulon 4HBX 384-well microtiter plates (Thermo part #8755) were coated with a 0.025 mg/mL solution of poly (Glu, Ala, Tyr; 6:3:1; Sigma P3899). Vari...				US Patent US9676783 (2017) BindingDB Entry DOI: 10.7270/Q26H4FK5
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