Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50479336'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479336 (CHEMBL517509) Show SMILES CN1CCN(CC(O)COc2ccc3oc(=O)cc(C)c3c2)CC1 Show InChI InChI=1S/C18H24N2O4/c1-13-9-18(22)24-17-4-3-15(10-16(13)17)23-12-14(21)11-20-7-5-19(2)6-8-20/h3-4,9-10,14,21H,5-8,11-12H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 1.0 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479336 (CHEMBL517509) Show SMILES CN1CCN(CC(O)COc2ccc3oc(=O)cc(C)c3c2)CC1 Show InChI InChI=1S/C18H24N2O4/c1-13-9-18(22)24-17-4-3-15(10-16(13)17)23-12-14(21)11-20-7-5-19(2)6-8-20/h3-4,9-10,14,21H,5-8,11-12H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.5 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479336 (CHEMBL517509) Show SMILES CN1CCN(CC(O)COc2ccc3oc(=O)cc(C)c3c2)CC1 Show InChI InChI=1S/C18H24N2O4/c1-13-9-18(22)24-17-4-3-15(10-16(13)17)23-12-14(21)11-20-7-5-19(2)6-8-20/h3-4,9-10,14,21H,5-8,11-12H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.1 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair