Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM159251'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM159251 (US9034874, 2.2) Show SMILES O=C(OC1CCN(CC1)c1cc[nH]c(=O)c1)N1CCN(CC1)C1CCC1 Show InChI InChI=1S/C19H28N4O3/c24-18-14-16(4-7-20-18)21-8-5-17(6-9-21)26-19(25)23-12-10-22(11-13-23)15-2-1-3-15/h4,7,14-15,17H,1-3,5-6,8-13H2,(H,20,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The potency of compounds of the invention as H3 receptor antagonists can be assessed by measuring the blockade of (R)-alpha-methylhistamine-mediated ...				US Patent US9034874 (2015) BindingDB Entry DOI: 10.7270/Q2C82819
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM159251 (US9034874, 2.2) Show SMILES O=C(OC1CCN(CC1)c1cc[nH]c(=O)c1)N1CCN(CC1)C1CCC1 Show InChI InChI=1S/C19H28N4O3/c24-18-14-16(4-7-20-18)21-8-5-17(6-9-21)26-19(25)23-12-10-22(11-13-23)15-2-1-3-15/h4,7,14-15,17H,1-3,5-6,8-13H2,(H,20,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
NOVARTIS AG US Patent					Assay Description The affinity of compounds of the invention to the H3 receptor can be assessed by measuring displacement of binding of the radioligand [3H]-N-alpha -M...				US Patent US9034874 (2015) BindingDB Entry DOI: 10.7270/Q2C82819
					More data for this Ligand-Target Pair