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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50051217'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50051217
PNG
(CHEMBL16142 | Phenyl-carbamic acid 3-(1H-imidazol-...)
Show SMILES O=C(Nc1ccccc1)OCCCc1cnc[nH]1
Show InChI InChI=1S/C13H15N3O2/c17-13(16-11-5-2-1-3-6-11)18-8-4-7-12-9-14-10-15-12/h1-3,5-6,9-10H,4,7-8H2,(H,14,15)(H,16,17)
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PC sid
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Similars

Article
PubMed
12.6n/an/an/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Binding affinity against Histamine H3 receptor on Synaptosomes from rat cerebral cortex was evaluated


J Med Chem 39: 1157-63 (1996)


Article DOI: 10.1021/jm9507688
BindingDB Entry DOI: 10.7270/Q2SF2V7G
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50051217
PNG
(CHEMBL16142 | Phenyl-carbamic acid 3-(1H-imidazol-...)
Show SMILES O=C(Nc1ccccc1)OCCCc1cnc[nH]1
Show InChI InChI=1S/C13H15N3O2/c17-13(16-11-5-2-1-3-6-11)18-8-4-7-12-9-14-10-15-12/h1-3,5-6,9-10H,4,7-8H2,(H,14,15)(H,16,17)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
14n/an/an/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
In vitro antagonistic activity of the compound against Histamine H3 receptor on Synaptosomes of rat cerebral cortex.


J Med Chem 39: 1157-63 (1996)


Article DOI: 10.1021/jm9507688
BindingDB Entry DOI: 10.7270/Q2SF2V7G
More data for this
Ligand-Target Pair