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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50051218'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50051218
PNG
((4-Trifluoromethoxy-phenyl)-carbamic acid 3-(1H-im...)
Show SMILES FC(F)(F)Oc1ccc(NC(=O)OCCCc2cnc[nH]2)cc1
Show InChI InChI=1S/C14H14F3N3O3/c15-14(16,17)23-12-5-3-10(4-6-12)20-13(21)22-7-1-2-11-8-18-9-19-11/h3-6,8-9H,1-2,7H2,(H,18,19)(H,20,21)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
 26n/an/an/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
In vitro antagonistic activity of the compound against Histamine H3 receptor on Synaptosomes of rat cerebral cortex.

J Med Chem 39: 1157-63 (1996)


Article DOI: 10.1021/jm9507688
BindingDB Entry DOI: 10.7270/Q2SF2V7G
More data for this
Ligand-Target Pair