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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50091393'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50091393
PNG
((4-(3-(1H-imidazol-4-yl)propyloxy)phenyl)ethanone ...)
Show SMILES CC(=NNC(N)=O)c1ccc(OCCCc2cnc[nH]2)cc1 |w:2.2|
Show InChI InChI=1S/C15H19N5O2/c1-11(19-20-15(16)21)12-4-6-14(7-5-12)22-8-2-3-13-9-17-10-18-13/h4-7,9-10H,2-3,8H2,1H3,(H,17,18)(H3,16,20,21)
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PC sid
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PubMed
 8.30n/an/an/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.

J Med Chem 43: 3335-43 (2000)


BindingDB Entry DOI: 10.7270/Q2RR1XGV
More data for this
Ligand-Target Pair