Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50139381'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139381 (4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCCC3)cc2c1 Show InChI InChI=1S/C22H22N2O/c23-16-17-4-6-18(7-5-17)19-8-9-22-20(14-19)15-21(25-22)10-13-24-11-2-1-3-12-24/h4-9,14-15H,1-3,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139381 (4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCCC3)cc2c1 Show InChI InChI=1S/C22H22N2O/c23-16-17-4-6-18(7-5-17)19-8-9-22-20(14-19)15-21(25-22)10-13-24-11-2-1-3-12-24/h4-9,14-15H,1-3,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139381 (4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCCC3)cc2c1 Show InChI InChI=1S/C22H22N2O/c23-16-17-4-6-18(7-5-17)19-8-9-22-20(14-19)15-21(25-22)10-13-24-11-2-1-3-12-24/h4-9,14-15H,1-3,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139381 (4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCCC3)cc2c1 Show InChI InChI=1S/C22H22N2O/c23-16-17-4-6-18(7-5-17)19-8-9-22-20(14-19)15-21(25-22)10-13-24-11-2-1-3-12-24/h4-9,14-15H,1-3,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair