Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50139395'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139395 (((R)-1-{2-[5-(4-Cyano-phenyl)-benzofuran-2-yl]-eth...) Show SMILES OC(=O)C[C@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H22N2O3/c24-15-16-3-5-17(6-4-16)18-7-8-22-19(12-18)13-21(28-22)9-11-25-10-1-2-20(25)14-23(26)27/h3-8,12-13,20H,1-2,9-11,14H2,(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139395 (((R)-1-{2-[5-(4-Cyano-phenyl)-benzofuran-2-yl]-eth...) Show SMILES OC(=O)C[C@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H22N2O3/c24-15-16-3-5-17(6-4-16)18-7-8-22-19(12-18)13-21(28-22)9-11-25-10-1-2-20(25)14-23(26)27/h3-8,12-13,20H,1-2,9-11,14H2,(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139395 (((R)-1-{2-[5-(4-Cyano-phenyl)-benzofuran-2-yl]-eth...) Show SMILES OC(=O)C[C@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H22N2O3/c24-15-16-3-5-17(6-4-16)18-7-8-22-19(12-18)13-21(28-22)9-11-25-10-1-2-20(25)14-23(26)27/h3-8,12-13,20H,1-2,9-11,14H2,(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139395 (((R)-1-{2-[5-(4-Cyano-phenyl)-benzofuran-2-yl]-eth...) Show SMILES OC(=O)C[C@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H22N2O3/c24-15-16-3-5-17(6-4-16)18-7-8-22-19(12-18)13-21(28-22)9-11-25-10-1-2-20(25)14-23(26)27/h3-8,12-13,20H,1-2,9-11,14H2,(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair