Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50139411'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139411 ((6-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H31N3O3/c1-18-3-4-19(2)29(18)10-9-23-16-22-15-20(6-8-25(22)32-23)24-7-5-21(17-27-24)26(30)28-11-13-31-14-12-28/h5-8,15-19H,3-4,9-14H2,1-2H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139411 ((6-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H31N3O3/c1-18-3-4-19(2)29(18)10-9-23-16-22-15-20(6-8-25(22)32-23)24-7-5-21(17-27-24)26(30)28-11-13-31-14-12-28/h5-8,15-19H,3-4,9-14H2,1-2H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139411 ((6-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H31N3O3/c1-18-3-4-19(2)29(18)10-9-23-16-22-15-20(6-8-25(22)32-23)24-7-5-21(17-27-24)26(30)28-11-13-31-14-12-28/h5-8,15-19H,3-4,9-14H2,1-2H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50139411 ((6-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H31N3O3/c1-18-3-4-19(2)29(18)10-9-23-16-22-15-20(6-8-25(22)32-23)24-7-5-21(17-27-24)26(30)28-11-13-31-14-12-28/h5-8,15-19H,3-4,9-14H2,1-2H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair