Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50317676'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50317676 ((4-cyclobutyl-1,4-diazepan-1-yl)((2S,4S)-1-cyclopr...) Show SMILES Fc1ccc(O[C@H]2C[C@H](N(C2)C2CC2)C(=O)N2CCCN(CC2)C2CCC2)cc1 |r| Show InChI InChI=1S/C23H32FN3O2/c24-17-5-9-20(10-6-17)29-21-15-22(27(16-21)19-7-8-19)23(28)26-12-2-11-25(13-14-26)18-3-1-4-18/h5-6,9-10,18-19,21-22H,1-4,7-8,11-16H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Binding affinity to human histamine H3 receptor				Bioorg Med Chem Lett 20: 2755-60 (2010) Article DOI: 10.1016/j.bmcl.2010.03.071 BindingDB Entry DOI: 10.7270/Q2Z60P7S
					More data for this Ligand-Target Pair