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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50325476'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50325476
PNG
(1-(1-(2-(1-(pyridin-4-ylmethyl)piperidin-4-yl)acet...)
Show SMILES O=C(CC1CCN(Cc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C25H31N5O2/c31-24(17-19-7-13-28(14-8-19)18-20-5-11-26-12-6-20)29-15-9-21(10-16-29)30-23-4-2-1-3-22(23)27-25(30)32/h1-6,11-12,19,21H,7-10,13-18H2,(H,27,32)
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PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 180n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair