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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50325477'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50325477
PNG
(1-(1-((1-(pyridin-4-ylmethyl)piperidin-4-yl)methyl...)
Show SMILES O=c1[nH]c2ccccc2n1C1CCN(CC2CCN(Cc3ccncc3)CC2)CC1
Show InChI InChI=1S/C24H31N5O/c30-24-26-22-3-1-2-4-23(22)29(24)21-9-15-28(16-10-21)18-20-7-13-27(14-8-20)17-19-5-11-25-12-6-19/h1-6,11-12,20-21H,7-10,13-18H2,(H,26,30)
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Article
PubMed
 24n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair