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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50383453'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50383453
PNG
(CHEMBL2031613)
Show SMILES O=c1ccc2cc(ccc2[nH]1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C21H25N5OS/c27-19-7-5-15-14-16(4-6-18(15)22-19)20-23-24-21(28-20)26-12-8-17(9-13-26)25-10-2-1-3-11-25/h4-7,14,17H,1-3,8-13H2,(H,22,27)
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Similars
Article
PubMed
 10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...

Bioorg Med Chem Lett 22: 3354-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.076
BindingDB Entry DOI: 10.7270/Q2DN462S
More data for this
Ligand-Target Pair