Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50404283'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50404283 (CHEMBL2112921) Show SMILES O[C@@H]1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 |r| Show InChI InChI=1S/C25H28N2O4/c28-22-7-9-26(17-22)10-8-23-16-21-15-20(5-6-24(21)31-23)18-1-3-19(4-2-18)25(29)27-11-13-30-14-12-27/h1-6,15-16,22,28H,7-14,17H2/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50404283 (CHEMBL2112921) Show SMILES O[C@@H]1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 |r| Show InChI InChI=1S/C25H28N2O4/c28-22-7-9-26(17-22)10-8-23-16-21-15-20(5-6-24(21)31-23)18-1-3-19(4-2-18)25(29)27-11-13-30-14-12-27/h1-6,15-16,22,28H,7-14,17H2/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50404283 (CHEMBL2112921) Show SMILES O[C@@H]1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 |r| Show InChI InChI=1S/C25H28N2O4/c28-22-7-9-26(17-22)10-8-23-16-21-15-20(5-6-24(21)31-23)18-1-3-19(4-2-18)25(29)27-11-13-30-14-12-27/h1-6,15-16,22,28H,7-14,17H2/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50404283 (CHEMBL2112921) Show SMILES O[C@@H]1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 |r| Show InChI InChI=1S/C25H28N2O4/c28-22-7-9-26(17-22)10-8-23-16-21-15-20(5-6-24(21)31-23)18-1-3-19(4-2-18)25(29)27-11-13-30-14-12-27/h1-6,15-16,22,28H,7-14,17H2/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranes				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair