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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50510715'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50510715
PNG
(CHEMBL4544939)
Show SMILES Clc1ccc(Cn2ccc3c(ncnc23)N2CCC(CC2)N2CCCCC2)cc1
Show InChI InChI=1S/C23H28ClN5/c24-19-6-4-18(5-7-19)16-29-15-10-21-22(25-17-26-23(21)29)28-13-8-20(9-14-28)27-11-2-1-3-12-27/h4-7,10,15,17,20H,1-3,8-9,11-14,16H2
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 26n/an/an/an/an/an/an/an/a



Heinrich Heine University D£sseldorf

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK-293 cells incubated for 90 mins by radioligand displace...

Bioorg Med Chem 27: 3194-3200 (2019)


Article DOI: 10.1016/j.bmc.2019.05.042
BindingDB Entry DOI: 10.7270/Q2P84G6K
More data for this
Ligand-Target Pair