BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50510718'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50510718
PNG
(CHEMBL4573388)
Show SMILES Nc1nc(N2CCC(CC2)N2CCCCC2)c2ccn(CCN3CCOCC3)c2n1
Show InChI InChI=1S/C22H35N7O/c23-22-24-20(28-9-4-18(5-10-28)27-7-2-1-3-8-27)19-6-11-29(21(19)25-22)13-12-26-14-16-30-17-15-26/h6,11,18H,1-5,7-10,12-17H2,(H2,23,24,25)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 121n/an/an/an/an/an/an/an/a



Heinrich Heine University D£sseldorf

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK-293 cells incubated for 90 mins by radioligand displace...

Bioorg Med Chem 27: 3194-3200 (2019)


Article DOI: 10.1016/j.bmc.2019.05.042
BindingDB Entry DOI: 10.7270/Q2P84G6K
More data for this
Ligand-Target Pair