BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50510719'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50510719
PNG
(CHEMBL4436457)
Show SMILES Clc1ccc(Cn2ccc3c(nc(Cl)nc23)N2CCC(CC2)N2CCCCC2)cc1
Show InChI InChI=1S/C23H27Cl2N5/c24-18-6-4-17(5-7-18)16-30-15-10-20-21(26-23(25)27-22(20)30)29-13-8-19(9-14-29)28-11-2-1-3-12-28/h4-7,10,15,19H,1-3,8-9,11-14,16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
42n/an/an/an/an/an/an/an/a



Heinrich Heine University D£sseldorf

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK-293 cells incubated for 90 mins by radioligand displace...


Bioorg Med Chem 27: 3194-3200 (2019)


Article DOI: 10.1016/j.bmc.2019.05.042
BindingDB Entry DOI: 10.7270/Q2P84G6K
More data for this
Ligand-Target Pair