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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50510724'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50510724
PNG
(CHEMBL4560119)
Show SMILES Clc1nc(N2CCC(CC2)N2CCCCC2)c2ccn(Cc3c(Cl)cccc3Cl)c2n1
Show InChI InChI=1S/C23H26Cl3N5/c24-19-5-4-6-20(25)18(19)15-31-14-9-17-21(27-23(26)28-22(17)31)30-12-7-16(8-13-30)29-10-2-1-3-11-29/h4-6,9,14,16H,1-3,7-8,10-13,15H2
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 54n/an/an/an/an/an/an/an/a



Heinrich Heine University D£sseldorf

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK-293 cells incubated for 90 mins by radioligand displace...

Bioorg Med Chem 27: 3194-3200 (2019)


Article DOI: 10.1016/j.bmc.2019.05.042
BindingDB Entry DOI: 10.7270/Q2P84G6K
More data for this
Ligand-Target Pair