Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50538681'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50538681 (CHEMBL4595327) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccnc(NCC(C)(C)C)n1 |r| Show InChI InChI=1S/C15H27N5/c1-15(2,3)11-17-14-16-8-6-13(18-14)20-9-7-12(10-20)19(4)5/h6,8,12H,7,9-11H2,1-5H3,(H,16,17,18)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of UR-DEBa242 binding to human recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...				J Med Chem 63: 5297-5311 (2020) Article DOI: 10.1021/acs.jmedchem.0c00160 BindingDB Entry DOI: 10.7270/Q2WM1HZ1
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50538681 (CHEMBL4595327) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccnc(NCC(C)(C)C)n1 |r| Show InChI InChI=1S/C15H27N5/c1-15(2,3)11-17-14-16-8-6-13(18-14)20-9-7-12(10-20)19(4)5/h6,8,12H,7,9-11H2,1-5H3,(H,16,17,18)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from Galphai2/Gbeta1gamma2-coupled human recombinant H4R expressed in baculovirus infected Sf9 insect cell membranes				J Med Chem 63: 5297-5311 (2020) Article DOI: 10.1021/acs.jmedchem.0c00160 BindingDB Entry DOI: 10.7270/Q2WM1HZ1
					More data for this Ligand-Target Pair
Histamine H4 receptor (Mus musculus (mouse))	BDBM50538681 (CHEMBL4595327) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccnc(NCC(C)(C)C)n1 |r| Show InChI InChI=1S/C15H27N5/c1-15(2,3)11-17-14-16-8-6-13(18-14)20-9-7-12(10-20)19(4)5/h6,8,12H,7,9-11H2,1-5H3,(H,16,17,18)/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of UR-DEBa242 binding to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...				J Med Chem 63: 5297-5311 (2020) Article DOI: 10.1021/acs.jmedchem.0c00160 BindingDB Entry DOI: 10.7270/Q2WM1HZ1
					More data for this Ligand-Target Pair
Histamine H4 receptor (Mus musculus (mouse))	BDBM50538681 (CHEMBL4595327) Show SMILES CN(C)[C@@H]1CCN(C1)c1ccnc(NCC(C)(C)C)n1 |r| Show InChI InChI=1S/C15H27N5/c1-15(2,3)11-17-14-16-8-6-13(18-14)20-9-7-12(10-20)19(4)5/h6,8,12H,7,9-11H2,1-5H3,(H,16,17,18)/t12-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Agonist activity at mouse recombinant H4R expressed in HEK293T cells by beta-arrestin recruitment assay				J Med Chem 63: 5297-5311 (2020) Article DOI: 10.1021/acs.jmedchem.0c00160 BindingDB Entry DOI: 10.7270/Q2WM1HZ1
					More data for this Ligand-Target Pair