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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase KAT2B' and Ligand = 'BDBM371530'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371530
PNG
((racemic)-4-chloro-2-methyl-5-(quinuclidin-3-ylami...)
Show SMILES Cn1ncc(NC2CN3CCC2CC3)c(Cl)c1=O |(4.67,-.77,;3.33,,;3.33,1.54,;2,2.31,;.67,1.54,;-.67,2.31,;-2,1.54,;-2,,;-3.33,-.77,;-3.97,.19,;-3.97,1.35,;-3.33,2.31,;-4.67,1.54,;-4.67,,;.67,,;-.67,-.77,;2,-.77,;2,-2.31,)|
Show InChI InChI=1S/C12H17ClN4O/c1-16-12(18)11(13)9(6-14-16)15-10-7-17-4-2-8(10)3-5-17/h6,8,10,15H,2-5,7H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 975n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair