Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase KAT2B' and Ligand = 'BDBM371552'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM371552 (4-chloro-5-((1-isopropylpiperidin-3-yl)amino)-2-me...) Show SMILES CC(C)N1CCCC(C1)Nc1cnn(C)c(=O)c1Cl Show InChI InChI=1S/C13H21ClN4O/c1-9(2)18-6-4-5-10(8-18)16-11-7-15-17(3)13(19)12(11)14/h7,9-10,16H,4-6,8H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc.					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				J Med Chem 48: 3919-29 (2005) BindingDB Entry DOI: 10.7270/Q2X06991
					More data for this Ligand-Target Pair