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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase KAT2B' and Ligand = 'BDBM371556'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B


(Homo sapiens (Human))		BDBM371556
PNG
(4-chloro-2-methyl-5-((1-((S)-1-phenylethyl)piperid...)
Show SMILES C[C@H](N1CCCC(C1)Nc1cnn(C)c(=O)c1Cl)c1ccccc1 |r|
Show InChI InChI=1S/C18H23ClN4O/c1-13(14-7-4-3-5-8-14)23-10-6-9-15(12-23)21-16-11-20-22(2)18(24)17(16)19/h3-5,7-8,11,13,15,21H,6,9-10,12H2,1-2H3/t13-,15?/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 631n/an/an/an/an/an/a



GLSynthesis Inc.



Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

J Med Chem 48: 3919-29 (2005)


BindingDB Entry DOI: 10.7270/Q2X06991
More data for this
Ligand-Target Pair