Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50524838'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50524838 (CHEMBL4458726) Show SMILES COc1ccc(cc1)C1(O)N=C2N=CC=C3N2C1=Nc1ccccc31 |c:13,15,t:11,20| Show InChI InChI=1S/C19H14N4O2/c1-25-13-8-6-12(7-9-13)19(24)17-21-15-5-3-2-4-14(15)16-10-11-20-18(22-19)23(16)17/h2-11,24H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of fluorescein-labeled HIF-1alpha (786 to 826 residues) (unknown origin)/GST-fused p300 CH1 domain (323 to 423 residues) (unknown origin) ...				Bioorg Med Chem 27: 1145-1158 (2019) Article DOI: 10.1016/j.bmc.2019.01.042 BindingDB Entry DOI: 10.7270/Q2QC072Q
					More data for this Ligand-Target Pair
Histone acetyltransferase p300/Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50524838 (CHEMBL4458726) Show SMILES COc1ccc(cc1)C1(O)N=C2N=CC=C3N2C1=Nc1ccccc31 |c:13,15,t:11,20| Show InChI InChI=1S/C19H14N4O2/c1-25-13-8-6-12(7-9-13)19(24)17-21-15-5-3-2-4-14(15)16-10-11-20-18(22-19)23(16)17/h2-11,24H,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of HIF-1alpha- CTAD domain (unknown origin)/p300-CH1 domain (unknown origin) protein-protein interaction				J Med Chem 62: 5725-5749 (2019) Article DOI: 10.1021/acs.jmedchem.8b01596 BindingDB Entry DOI: 10.7270/Q2QF8X9V
					More data for this Ligand-Target Pair