Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone chaperone ASF1A' and Ligand = 'BDBM50101696'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101696 (CHEMBL3394905) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3cccnc3)cc2)cc(Br)c1O Show InChI InChI=1S/C21H17BrN4O4/c1-30-18-10-13(9-17(22)19(18)27)11-24-26-21(29)14-4-6-16(7-5-14)25-20(28)15-3-2-8-23-12-15/h2-12,27H,1H3,(H,25,28)(H,26,29)/b24-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair