Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase (HDAC1 and HDAC2)' and Ligand = 'BDBM50481010'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (HDAC1 and HDAC2) (Homo sapiens (Human))	BDBM50481010 (CHEMBL570279) Show SMILES COc1cc(CCC(=O)Nc2ccc(cc2)C(=O)NO)ccc1OCc1ccc(C)cc1 Show InChI InChI=1S/C25H26N2O5/c1-17-3-5-19(6-4-17)16-32-22-13-7-18(15-23(22)31-2)8-14-24(28)26-21-11-9-20(10-12-21)25(29)27-30/h3-7,9-13,15,30H,8,14,16H2,1-2H3,(H,26,28)(H,27,29)	PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetry				Eur J Med Chem 44: 4470-6 (2009) Article DOI: 10.1016/j.ejmech.2009.06.010 BindingDB Entry DOI: 10.7270/Q2P55RB1
					More data for this Ligand-Target Pair