Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50137833'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50137833 (6-(5-Hydroxy-6-morpholin-4-ylmethyl-1,3-dioxo-1,3-...) Show SMILES Nc1ccccc1NC(=O)CCCCCN1C(=O)c2cc(O)c(CN3CCOCC3)cc2C1=O Show InChI InChI=1S/C25H30N4O5/c26-20-6-3-4-7-21(20)27-23(31)8-2-1-5-9-29-24(32)18-14-17(16-28-10-12-34-13-11-28)22(30)15-19(18)25(29)33/h3-4,6-7,14-15,30H,1-2,5,8-13,16,26H2,(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Ability to inhibit recombinant human histone deacetylase 1 (HDAC-1).				Bioorg Med Chem Lett 14: 283-7 (2003) BindingDB Entry DOI: 10.7270/Q2BV7G17
					More data for this Ligand-Target Pair