Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 11 (Homo sapiens (Human)) | BDBM421500 (US10508088, Example 1-1 | US10508088, ID HDTK010 |...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
FORMA Therapeutics, Inc. US Patent | Assay Description This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a... | US Patent US10508088 (2019) BindingDB Entry DOI: 10.7270/Q2280B04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 11 (Homo sapiens (Human)) | BDBM421500 (US10508088, Example 1-1 | US10508088, ID HDTK010 |...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | n/a |
FORMA Therapeutics, Inc.; H. Lee Moffitt Cancer Center and Research Institute, Inc. US Patent | Assay Description The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ... | US Patent US10538496 (2020) BindingDB Entry DOI: 10.7270/Q24J0HJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 11 (Homo sapiens (Human)) | BDBM421500 (US10508088, Example 1-1 | US10508088, ID HDTK010 |...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <500 | n/a | n/a | n/a | n/a | n/a | n/a |
FORMA Therapeutics, Inc. US Patent | Assay Description This example describes in vitro inhibition properties of exemplary HDAC11 inhibitors for various HDACs. HDAC inhibition assays were performed using a... | US Patent US10508088 (2019) BindingDB Entry DOI: 10.7270/Q2280B04 | |||||||||||
More data for this Ligand-Target Pair |