Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM375726'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375726 (US10301323, Compound D3 | US9908899, Compound D3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccccc2)c1 Show InChI InChI=1S/C20H20N4O2/c21-18-8-4-5-9-19(18)23-20(25)11-10-16-14-22-24(15-16)12-13-26-17-6-2-1-3-7-17/h1-11,14-15H,12-13,21H2,(H,23,25)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM375726 (US10301323, Compound D3 | US9908899, Compound D3) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(CCOc2ccccc2)c1 Show InChI InChI=1S/C20H20N4O2/c21-18-8-4-5-9-19(18)23-20(25)11-10-16-14-22-24(15-16)12-13-26-17-6-2-1-3-7-17/h1-11,14-15H,12-13,21H2,(H,23,25)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 50: 685-95 (2007) BindingDB Entry DOI: 10.7270/Q2736T75
					More data for this Ligand-Target Pair