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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM50259811'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 2


(Homo sapiens (Human))		BDBM50259811
PNG
(CHEMBL4066975)
Show SMILES COc1ccc(cc1)C(=O)c1cn(Cc2ccc(cc2)C(=O)NO)c2cc(OC)ccc12
Show InChI InChI=1S/C25H22N2O5/c1-31-19-9-7-17(8-10-19)24(28)22-15-27(23-13-20(32-2)11-12-21(22)23)14-16-3-5-18(6-4-16)25(29)26-30/h3-13,15,30H,14H2,1-2H3,(H,26,29)
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MMDB

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Similars
Article
PubMed
n/an/a 209n/an/an/an/an/an/a



Taipei Medical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human HDAC2 using fluorogenic substrate by fluorescence assay

Eur J Med Chem 125: 1268-1278 (2017)


Article DOI: 10.1016/j.ejmech.2016.11.033
BindingDB Entry DOI: 10.7270/Q2XD145D
More data for this
Ligand-Target Pair