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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM50509454'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 2


(Homo sapiens (Human))		BDBM50509454
PNG
(CHEMBL4440413)
Show SMILES CN(C)c1ccc(cc1)C(=O)N(CCCCCC(=O)Nc1ccccc1N)CC(=O)NCc1ccccc1
Show InChI InChI=1S/C30H37N5O3/c1-34(2)25-18-16-24(17-19-25)30(38)35(22-29(37)32-21-23-11-5-3-6-12-23)20-10-4-7-15-28(36)33-27-14-9-8-13-26(27)31/h3,5-6,8-9,11-14,16-19H,4,7,10,15,20-22,31H2,1-2H3,(H,32,37)(H,33,36)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.24E+3n/an/an/an/an/an/a



Heinrich-Heine-Universit£t D£sseldorf

Curated by ChEMBL


Assay Description
Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-ace...

J Med Chem 62: 11260-11279 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01489
BindingDB Entry DOI: 10.7270/Q2JW8J5F
More data for this
Ligand-Target Pair