Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM50525406 (CHEMBL164868) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
UMR CNRS 7285 Curated by ChEMBL | Assay Description Inhibition of human recombinant HDAC3 using fluorogenic HDAC substrate measured after 10 mins by fluorimetry assay | ACS Med Chem Lett 10: 863-868 (2019) Article DOI: 10.1021/acsmedchemlett.8b00440 BindingDB Entry DOI: 10.7270/Q23J3HDS | |||||||||||
More data for this Ligand-Target Pair |