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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 5' and Ligand = 'BDBM50525406'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 5


(Homo sapiens (Human))		BDBM50525406
PNG
(CHEMBL164868)
Show SMILES C[C@@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C
Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m0/s1
KEGG

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MCE
PC cid
PC sid
PDB
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Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



UMR CNRS 7285

Curated by ChEMBL


Assay Description
Inhibition of human recombinant HDAC5 using fluorogenic HDAC substrate class 2a measured after 30 mins by fluorimetry assay

ACS Med Chem Lett 10: 863-868 (2019)


Article DOI: 10.1021/acsmedchemlett.8b00440
BindingDB Entry DOI: 10.7270/Q23J3HDS
More data for this
Ligand-Target Pair