Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50517584'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517584 (CHEMBL4447453) Show SMILES ONC(=O)c1ccc(CN2N=C(Cl)C=C3Sc4ccccc4N=C23)cc1 |t:10,13,23| Show InChI InChI=1S/C18H13ClN4O2S/c19-16-9-15-17(20-13-3-1-2-4-14(13)26-15)23(21-16)10-11-5-7-12(8-6-11)18(24)22-25/h1-9,25H,10H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair